Endocrine Abstracts

Introduction: Parathyroid carcinoma and atypical parathyroid adenoma are among rarely encountered causes of primary hyperparathyroidism. Patients with parathyroid carcinoma often differ from those with atypical parathyroid adenoma or parathyromatosis at the time of presentation because patients with parathyroid carcinoma have more profound hypercalcemia as well as invasive tumors. However, at times, it is difficult to distinguish between these conditions both clinically and by...

Introduction: We report a case of papillary thyroid carcinoma recurrence. According to most of the guidelines, patients with PTC have recurrences in the first 5 years after diagnosis and the most rigorous follow-up is indicated in this time; however metastasis are reported beyond this period and are associated mostly with lack of adherence to follow-up.Case report: A 76-year-old female was admitted in our department for the evaluation of a 5 cm laterocer...

Osteopetrosis and O.I. are both bone metabolic disorders with opposite features in terms of the metabolic turnover: while osteopetrozis has a low turnover and increased BMD due to the failure of osteoclasts to resorb bone, O.I. is well known as a high turnover disease with low BMD caused bt mutations in the COL1A1 and col COL1A2 genes that encode type 1 procollagen; yet, both condition, in spite of different mechanism, end up with increased ftracure prevalence. We report the c...

Introduction: As the incidence of thyroid cancer is increasing, so are the cases of recurrence with RAI refractory metastasis of thyroid differentiated cancer. We present such a caseCase report: A 77-year-old female with a medical history of papillary thyroid carcinoma recurrence 10 years after surgery with successful 3 RAI sessions and normal thyroid cancer markers after treatment until her recurrence a year ago, with TSH unstimulated thyroglobulin of 1...

Introduction: Papillary thyroid carcinoma is well known as a differentiated thyroid carcinoma with an established treatment protocol and high survival rates. Poorly differentiated thyroid carcinoma, or anaplastic, is highly aggressive, manifesting with local invasion, recurrence, and distant metastasis; it is well known that these two entities may be connected as a process of dedifferentiation, most commonly met in elderly people with a long term standing untreated well differ...

Introduction: The aim of the study was to evaluate the relevance of autoimmunity in the cytological results for the thyroid nodules referred to FNAB (fine-needle aspiration biopsy).Materials and methods: Our study included 590 patients who underwent FNAC in 615 nodules between December 2015 and January 2019. Besides demographic data and routine endocrine investigations (thyroid hormonal status, presence of autoimmunity, the actual or past use of levothyr...

Introduction: The FRAX fracture risk assessment algorithm is able to integrate clinical risk factors independent of bone mineral density (BMD), evaluating the 10-years probability of fracture, therefore identifying patients in need for antiosteoporotic treatment, in which case bypassing the WHO (World Health Organization) criteria for densitometric diagnosis of osteoporosis.Material and Methods: We retrospectively analysed a total of 91 scans of women ag...

Introduction: Besides the amount of bone mineral assesed through bone mineral density (BMD), studies have shown that neck geometry parameters as hip axis length (HAL) and neck-shaft angle (NSA) could also be reliable parameters to be included in the hip fracture assesement. On the other hand, bone geometry is known to be modified in acromegaly in flat bones, thus hip fracture is not a recognized direct complication in acromegaly neither through bone mass or long bone geometry....

Introduction: Diabetes mellitus and acromegaly are both associated with an increased risk of fracture caused by altered quality of bone. TBS represents an important tool for assessment of bone microarchitecture.Objectives: The aim of this study is to assess the bone deterioration through the trabecular bone score (TBS) and to compare TBS and Z score between 2 groups of patients: acromegaly and diabetes mellitus.Methods: This retros...